In response to Point:Counterpoint: "Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy".
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Last Word on Point:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy.
To the Editor: The authors of the Point:Counterpoint debate (1, 2) collectively thank our colleagues for their thoughtful responses to the topic “Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy.” While the goal of our initial position piece and rebuttal was to selectively present published data in a manner that supported our argument, all the authors recognize the l...
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Ursolic acid (UA) is known as a naturally occurring triterpene pentacyclic compound in some medicinal herbs including savory that affects the skeletal muscle. In the current study, the effect of UA was evaluated on C2C12 cells and satellite cells (SCs) isolated from native broiler chicks. First in the in vitro experiment, the C2C12 cell line obtained from the Stem Cell Technology Research Cente...
متن کاملCounterpoint: Satellite cell addition is not obligatory for skeletal muscle hypertrophy.
domain ceiling " exists such that additional increases in myofiber cross-sectional area require myonuclear addition. Accordingly, satellite cell-independent and-dependent phases of myofiber growth occur as shown by analyzing irradiated soleus muscles at multiple time points after a growth stimulus (17). As distinct phases of muscle growth exist, multiple time points are necessary to conclusivel...
متن کاملPoint:Counterpoint: Satellite cell addition is/is not obligatory for skeletal muscle hypertrophy.
Myofiber size is dynamically regulated, increasing and decreasing depending on muscle use. Hypertrophy is defined by increases in myofiber cross-sectional area and mass as well as myofibrillar protein content. Myofibers contain many hundreds of nuclei, each of which has a nuclear domain. A nuclear domain is the volume of cytoplasm within the myofiber regulated by the gene products of a single m...
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Introduction: Satellite cells are known as the main regenerative cell type in skeletal muscles. Our study established a modified digestion and preplating method for the isolation of slow or weak adherent cells for the enrichment of satellite cells. Low-survival rate of these primary stem cells prompted us to address whether cell culture medium substitution might change cell viability status. M...
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عنوان ژورنال:
- Journal of applied physiology
دوره 103 3 شماره
صفحات -
تاریخ انتشار 2007